One of Central Jersey’s biggest medical campuses is expanding in a major way, as work has begun on a 200,000-square-foot cancer treatment facility in Middlesex County.
Penn Medicine leaders and regional community representatives recently broke ground on the Penn Medicine Princeton Cancer Center in Plainsboro, which will deliver a full spectrum of cancer services to patients when completed. The future 200,000-square-foot center will rise five stories and include a recently completed six-story parking structure.
“A cancer diagnosis disrupts routines and introduces a level of uncertainty that touches everything in a patient’s life,” said Kevin B. Mahoney, CEO of the University of Pennsylvania Health System. “The Penn Medicine Princeton Cancer Center will help us deliver cutting-edge research and clinical innovations to Central New Jersey, ensuring care that is close to home, carefully coordinated, and deeply compassionate.”
The move represents the largest expansion of Princeton Health since the new hospital opened in 2012. The new cancer center will house more than 40 exam rooms, 30 infusion chairs, and two linear accelerators to deliver radiation therapy.
The center will also feature a breast imaging center and advanced diagnostic technologies, including CT, MRI, and SPECT/CT, which provides clearer images at lower radiation doses and enables physicians to both detect cancer earlier and guide treatment with greater precision.
“This is a significant first step in our efforts to redefine cancer care in Central New Jersey,” said Princeton Health CEO James Demetriades. “The Penn Medicine Princeton Cancer Center will offer patients seamless access to clinical trials, personalized therapies, and coordinated care across our entire health system.”
The Cancer Center will feature a blend of forward-thinking design with environmental stewardship, targeting prestigious LEED Gold certification and continuing the system’s efforts to become the nation’s most environmentally friendly health care organization. Green roofs will be incorporated across all canopies and oncology vaults to minimize the heat island effect, and rain gardens will capture excess water run-off.
With construction now underway, the new complex is expected to be completed and opened by May 2028.
